{"id":1858,"date":"2024-02-10T03:00:34","date_gmt":"2024-02-10T01:00:34","guid":{"rendered":"https:\/\/medicallib.co.za\/health-info\/?p=1858"},"modified":"2024-02-20T22:15:12","modified_gmt":"2024-02-20T20:15:12","slug":"what-is-ketamine","status":"publish","type":"post","link":"https:\/\/medicallib.co.za\/health-info\/what-is-ketamine\/","title":{"rendered":"What is Ketamine?"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.24.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-65px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.24.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; custom_margin=&#8221;-24px|auto||auto||&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.24.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.24.1&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;2em&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><span style=\"color: #333333;\">Ketamine (ketalar) is an injectable, fast-acting general anesthetic used as a sedative in humans and as a tranquilizer in animals. It is also classified as a \u201cdissociative anesthetic hallucinogen\u201d since it causes patients to feel cut off or disconnected from their pain and surroundings and not in control.<\/span><\/p>\n<p><span style=\"color: #333333;\">Ketamine is <span style=\"color: #3366ff;\"><a href=\"https:\/\/www.drugs.com\/mtm\/ketalar.html\" style=\"color: #3366ff;\">mostly utilized<\/a> <\/span>in surgery to induce sleep and minimize pain and suffering during specific diagnostic or therapeutic procedures. Also, lower doses of the drug are used in \u201c<strong>Ketamine therapy<\/strong>\u201d, a medical management procedure, to manage treatment-resistant depression, anxiety disorders, and post-traumatic stress disorder (PTSD). However, because Ketamine causes hallucinations and dissociation experiences at high doses, people abuse it to feel good, deal with life, or handle stress. Abuse has the potential to result in strong psychological dependence or moderate to low physical dependence. Ketamine has also been misused by facilitating sexual assault.<\/span><\/p>\n<p><span style=\"color: #333333;\">Lower doses of ketamine produce pain relief and sedation, while at higher dosages, the drug produces dissociation and hallucinatory effects. Levels for general anesthesia are typically in the 1,000-6,000 ng\/mL range.<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.24.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;2em&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><span style=\"color: #333333;\">Where does it come from?<\/span><\/h2>\n<p><span style=\"color: #333333;\">Many\u00a0countries produce ketamine for commercial use, including China, America, and India. Most of the ketamine that is illegally distributed comes from hospitals or veterinary practices. In countries like the United States, it is also illegally smuggled from Mexico.<\/span><\/p>\n<h2><span style=\"color: #333333;\">How does Ketamine look, smell, or taste?<\/span><\/h2>\n<p><span style=\"color: #333333;\">Commercial ketamine is produced as a clear liquid or as a white or off-white powder. But, when sold on the street, it is a crystalline powder that is gritty white, brown, or beige. Powdered ketamine (ranging from 100 to 200 milligrams) is commonly enclosed in tiny vials, tiny plastic bags, capsules, paper, glassine, or aluminum foil folds.<\/span><\/p>\n<p><span style=\"color: #333333;\">In order to increase weight and boost the dealer&#8217;s earnings, street ketamine is occasionally mixed or cut with other powders and sold as a white, brown, or beige crystalized powder. It is impossible to determine by appearance whether what you purchased has been tampered with.<\/span><\/p>\n<p><span style=\"color: #333333;\">Ketamine has an unappealingly bitter taste. <\/span><span style=\"color: #333333;\">The smell produced by heating up ketamine cigarettes is <span style=\"color: #3366ff;\"><a href=\"https:\/\/ieeexplore.ieee.org\/document\/8789497\" style=\"color: #3366ff;\">like burning plastic<\/a><\/span>. This makes it difficult to identify the drug based on smell.<\/span><\/p>\n<h2><span style=\"color: #333333;\">Classification<\/span><\/h2>\n<p><span style=\"color: #333333;\">Ketamine is classified as a Schedule III non-narcotic substance under the Controlled Substances Act. It does not act as an opiate, but <span style=\"color: #3366ff;\"><a href=\"https:\/\/www.pnas.org\/doi\/full\/10.1073\/pnas.1916570117\" style=\"color: #3366ff;\">its effects require an opiate receptor signaling pathway<\/a><\/span>.<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.24.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;2em&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><span style=\"color: #333333;\">How is Ketamine used or abused?<\/span><\/h2>\n<p><span style=\"color: #333333;\">Depending on its form, Ketamine can be injected, smoked (in marijuana or tobacco cigarettes), ingested (as a tablet, capsule, or mixed with drinks), or snorted. It is frequently combined with other drugs, such as cocaine or Ecstasy (also known as &#8220;kitty flipping&#8221;), amphetamine, or methamphetamine. Mixing with other drugs can result in fatal outcomes or death.<\/span><\/p>\n<h2><span style=\"color: #333333;\">How long before the effects of Ketamine kick off?<\/span><\/h2>\n<p><span style=\"color: #333333;\">Depending on how it is administered, ketamine&#8217;s effects can take time to manifest. When delivered intravenously (IV), ketamine takes effect in a matter of seconds; when injected intramuscularly (IM), it takes 4 minutes; when snooted or bumped, it takes 15 minutes; and when taken orally, it takes 20 to 60 minutes. Its effects might last for 5 to 60 minutes, depending on the dosage and method of administration.<\/span><\/p>\n<h2><span style=\"color: #333333;\">How long does Ketamine stay in the body?<\/span><\/h2>\n<p><span style=\"color: #333333;\">Many factors can impact how long a drug lasts and how quickly it is eliminated, including age, body mass, metabolic rate, drug dosage, and mode of administration. <span style=\"color: #3366ff;\"><a href=\"https:\/\/americanaddictioncenters.org\/ketamine-abuse\/how-long-does-ketamine-stay-in-your-system\" style=\"color: #3366ff;\">According to the American Addiction Centers<\/a><\/span>, after intake, ketamine can typically still be found in the blood for up to 72 hours, in saliva for up to 24 hours, in urine for up to 14 days, and in hair for up to one month or more.<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.24.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;2em&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><span style=\"color: #333333;\">What does Ketamine do to the body?<\/span><\/h2>\n<p><span style=\"color: #333333;\">A few minutes after taking Ketamine, blood pressure and heart rate may rise, then progressively drop over the course of the following 10 to 20 minutes. Users may become numb to stimulation. People who are in this state report experiencing muscle stiffness, salivation, tear secretions, dilated pupils, and involuntary fast eye movement. Other side effects include nausea, vomiting, abdominal pain (K cramp), or liver damage.<\/span><\/p>\n<p><span style=\"color: #333333;\">Ketamine affects the kidney, urinary tract, and bladder, leading to uncontrollable peeing. Serious damage to the bladder can occur, with an urgent and frequent need to pee and blood in the urine. The damage can be so severe that sometimes the bladder needs surgical repair or even removal.<\/span><\/p>\n<p><span style=\"color: #333333;\">Because Ketamine stops you from feeling pain, it increases your chances of injuring yourself without realizing it.<\/span><\/p>\n<p><span style=\"color: #333333;\">At higher dosages, Ketamine can slow down breathing, create numbness throughout the body, and cause mobility issues. An overdose can be lethal since it can cause breathing to stop, leading to death or unconsciousness. Acute effects of Ketamine have been linked to Matthew Perry\u2019s death, <span style=\"color: #3366ff;\"><a href=\"https:\/\/www.usatoday.com\/story\/entertainment\/celebrities\/2023\/12\/15\/matthew-perry-cause-of-death-revealed-ketamine\/71441112007\/\" style=\"color: #3366ff;\">according to medical reports, <\/a><\/span>whereby an overdose of the drug was detected.<\/span><\/p>\n<h2><span style=\"color: #333333;\">What does Ketamine do to the mind?<\/span><\/h2>\n<p><span style=\"color: #333333;\">Ketamine skews one&#8217;s perception of sound and vision. This induces hallucination, a sense of disconnection from reality, and a lack of control. The hallucinogenic effects don&#8217;t last very long\u2014between 30 and 60 minutes. Also, the effects give rise to different experiences for the user.<\/span><\/p>\n<p><span style=\"color: #333333;\">Slang terms for ketamine-related experiences or effects have been reported and include:<\/span><\/p>\n<ul>\n<li><span style=\"color: #333333;\">&#8220;K-land&#8221;, which denotes a tranquil and colorful experience.<\/span><\/li>\n<li><span style=\"color: #333333;\">&#8220;K-hole&#8221; is a term used to describe an out-of-body, near-death experience. This can last for up to 2 hours.<\/span><\/li>\n<li><span style=\"color: #333333;\">&#8220;Baby food&#8221;, which causes users to lapse into blissful, child-like inertia.<\/span><\/li>\n<li><span style=\"color: #333333;\">&#8220;God&#8221;, users who really believed they had encountered their creator.<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #333333;\">Side effects after taking Ketamine include hallucinogen persisting perception disorder (HPPD), agitation, depression, cognitive difficulties, unconsciousness, loss of memory (short and long-term), or an inability to concentrate. Hallucinogen Persisting Perception Disorder is reported to occur several weeks after consuming the drug.<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.24.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;2em&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><span style=\"color: #333333;\">How does Ketamine make people behave?<\/span><\/h2>\n<p><span style=\"color: #333333;\">It can cause people to appear calmer, slower, and more at ease, but it can also make it difficult for them to move normally and to make sense.<\/span><\/p>\n<h2><span style=\"color: #333333;\">Composition<\/span><\/h2>\n<p><span style=\"color: #333333;\">Ketamine is <span style=\"color: #3366ff;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7859674\/\" style=\"color: #3366ff;\">made up of a racemic mixture<\/a><\/span> that consists of equal amounts of two enantiomers, (S)-ketamine and (R)-ketamine (or esketamine and arketamine, respectively). The (S)-enantiomer called esketamine is a stronger form of Ketamine which is used as a nasal spray (Spravato\u00ae) for those with treatment-resistant depression. Esketamine is only available on prescription.<\/span><\/p>\n<h2><span style=\"color: #333333;\">Street names<\/span><\/h2>\n<p><span style=\"color: #333333;\">Common street names for ketamine include Cat Tranquilizer, Cat Valium, K, Jet K, Kit Kat, Purple, Special K, Special La Coke, Super Acid, Super K, Vitamin K, and Bump.<\/span><\/p>\n<h2><span style=\"color: #333333;\">Can you be addicted to Ketamine?<\/span><\/h2>\n<p><span style=\"color: #333333;\">Yes, you can be addicted. However, because ketamine does not cause any physical withdrawal symptoms, addiction to it is frequently referred to as psychological dependence. Dependence on the drug can lead to potential health risks. Contact an addiction center to help you stop.<\/span><\/p>\n<p><span style=\"color: #333333;\">Individuals who routinely use ketamine may become tolerant to it and need to take even more to achieve the desired results.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ketamine (ketalar) is an injectable, fast-acting general anesthetic used as a sedative in humans and as a tranquilizer in animals. It is also classified as a \u201cdissociative anesthetic hallucinogen\u201d since it causes patients to feel cut off or disconnected from their pain and surroundings and not in control. Ketamine is mostly utilized in surgery to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1872,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[170],"tags":[178,179,177,176],"class_list":["post-1858","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug","tag-addiction","tag-hallucination","tag-hallucinogen","tag-ketamine","et-has-post-format-content","et_post_format-et-post-format-standard"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What is Ketamine? | All you need to know!<\/title>\n<meta name=\"description\" content=\"Ketamine is an injectable, fast-acting general anesthetic used as a sedative in humans and animals. 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